Name | Pitavastatin calcium |
Synonyms | NK-104 Calcium Pitavasttin Calcium Pitavastatin calcium Pitavastatin calciuM(Livalo) Pitavastatin CalciuMDISCONTINUED Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl)-3,5-dihydroxyhept-6-enoate (+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-,5-dihydroxy-6-heptenoate} (+)-Monocalciunbis{(3r,5s,6e)-7-[2-cyclopropyl-4-(4-fluorophenyl-3-quinolyl]-3,5-dihydroxy-6-heptenotate} (+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate} calcium bis{(1R,3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-1,3,5-trihydroxyhept-6-en-1-olate} |
CAS | 147526-32-7 |
EINECS | 807-641-2 |
InChI | InChI=1/2C25H25FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,23,28-30H,5-6,13-14H2;/q2*-1;+2/b2*12-11+;/t2*18-,19-,23+;/m11./s1 |
Molecular Formula | C25H26CaFNO4 |
Molar Mass | 463.56 |
Melting Point | >138oC (dec.) |
Boling Point | 692℃ at 760 mmHg |
Specific Rotation(α) | D20 +23.1° (c = 1.00 in acetonitrile/water) |
Solubility | DMSO 51 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
Appearance | White to off-white powder |
Color | White to Off-White |
Storage Condition | 2-8°C |
Stability | Hygroscopic |
Physical and Chemical Properties | Properties: White or almost white crystalline powder specific rotation: 14~22 °; PH 5.6-7.2 |
Use | Therapeutic drug for hyperlipidemia |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29339900 |
Toxicity | LDLo orl-rat: 500 mg/kg OYYAA2 56,67,1998 |
Reference Show more | 1. Zhang Min, Ju Aixia, Li Yangyang, et al. Effect of Breviscapine on Atorvastatin Drug Transport in Vivo [J]. Chemical Engineer, 2019, v.33;No.282(03):81-86. |